Norepinephrine is infusing through a peripheral IV. The site… | MyMerci
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Medication Administration PPT
Question

Norepinephrine is infusing through a peripheral IV. The site becomes pale, cool, swollen, and painful. Which action should the nurse take?

Explanation
Pallor, coolness, swelling, and pain at a peripheral norepinephrine site indicate extravasation with risk of ischemia and tissue necrosis. Stop infusion through that catheter without flushing, leave it in place initially for aspiration, notify the provider, and prepare prompt phentolamine infiltration according to protocol. Resume vasopressor support through new appropriate access while the affected site is treated and monitored.
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In-depth explanation

Clinical reasoning
Norepinephrine produces intense alpha-adrenergic vasoconstriction. In subcutaneous tissue, that effect can rapidly cause ischemia, sloughing, and necrosis.

Decision rule
Stop delivery into the injured site, do not flush, aspirate through the existing catheter when possible, and treat urgently with protocol-directed phentolamine. Establish new access promptly so hemodynamic support can continue safely.
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For study reference only. Always follow current clinical guidelines and your institution’s protocols.