A client taking lisinopril develops sudden swelling of the l… | MyMerci
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Medication Administration PPT
Question

A client taking lisinopril develops sudden swelling of the lips and tongue with hoarseness and difficulty swallowing. Which action should the nurse take?

Explanation
Lisinopril can cause angioedema involving the lips, tongue, glottis, or larynx at any time during treatment. Hoarseness and difficulty swallowing indicate possible airway obstruction. Lisinopril is discontinued promptly, emergency care is activated, oxygenation is supported, and equipment and personnel for definitive airway management are prepared. Oral medication and delayed observation are inadequate.
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In-depth explanation

Clinical reasoning
ACE inhibitor angioedema is mediated largely by bradykinin and can progress rapidly to upper-airway obstruction. Visible swelling may underestimate laryngeal involvement.

Decision rule
Tongue swelling, hoarseness, dysphagia, or breathing difficulty while taking an ACE inhibitor is an airway emergency: discontinue the drug, call for emergency support, and prepare a definitive airway.
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