A 82-year-old presents to clinic with recent falls and worsening confusion. After reviewing the EHR (History, Vitals, Labs, Notes, Orders), which medication should the nurse advocate to discuss with the provider as the highest priority deprescribing target per Beers criteria?

Diphenhydramine is on the AGS Beers list of potentially inappropriate medications (PIMs) in older adults: strong anticholinergic burden causes confusion, sedation, urinary retention, dry mouth, and increases fall and dementia risk. It should be avoided as a sleep aid in adults ≥ 65. Lisinopril, metformin, and atorvastatin are appropriate for ongoing chronic disease management at usual doses (with monitoring) and not Beers-flagged in this scenario.