A PaO2/FiO2 ratio of 110 with bilateral infiltrates and no cardiogenic origin meets Berlin criteria for moderate ARDS (P/F 100–200) approaching severe (<100). For moderate-to-severe ARDS, prone positioning for 12–16 hours per day improves ventilation–perfusion matching by recruiting collapsed dorsal lung regions, redistributing perfusion, and reducing ventilator-induced lung injury. The PROSEVA trial and subsequent meta-analyses showed a mortality benefit. Choice 1 confuses prone positioning with vasodilator therapy. Choice 3 trivializes a major intervention. Choice 4 inverts the sequence — prone positioning is tried before ECMO, not after.
ARDS Berlin criteria require acute onset within one week, bilateral infiltrates on imaging, edema not fully explained by cardiac failure or volume overload, and a PaO2/FiO2 ratio defining severity — mild 200–300, moderate 100–200, severe <100, all on PEEP at least 5. The mechanism of prone positioning is recruitment of dorsal (dependent) lung regions, redistribution of perfusion away from overdistended ventral regions, and reduction of ventilator-induced lung injury. Recommended duration is 12–16 hours per day for moderate-to-severe ARDS (P/F <150); the PROSEVA trial demonstrated a mortality reduction. Nursing pre-positioning checklist: secure ETT, lines, and tubes; pad pressure points; suction; maintain head and neck alignment; reverse Trendelenburg slightly; perform the maneuver as a team. Monitor for facial edema, pressure injuries, tube displacement, hemodynamic changes, and feeding tolerance. Common complications: facial edema, corneal injury, brachial plexus injury, and line occlusion.
<p>A patient on mechanical ventilation has <strong>bilateral infiltrates</strong> on CXR, <strong>no signs of cardiogenic edema</strong>, <strong>FiO2 0.80</strong>, <strong>PEEP 12</strong>, and a <strong>PaO2 88 mm Hg</strong> (<strong>PaO2/FiO2 110</strong>). The provider orders <strong>prone positioning</strong>.</p>
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