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Sleep restores the body and brain, consolidates memory, supports immune function, and regulates mood and metabolism. Two processes control it: the circadian rhythm (a roughly 24-hour clock in the hypothalamus, set mainly by light and signaled by melatonin release in darkness) and sleep pressure that builds the longer a person is awake.
Sleep stages (current scoring combines the older stages 3 and 4 into a single N3 stage)
| Stage | Features |
|---|---|
| N1 | Light transition sleep; easily awakened |
| N2 | Largest share of the night; heart rate and temperature fall |
| N3 (slow-wave, deep sleep) | Hardest to awaken; growth hormone release, tissue repair; sleepwalking and night terrors arise here |
| REM | Rapid eye movements, vivid dreaming, muscle paralysis (atonia), variable heart rate and BP, brain activity similar to waking; important for memory and mood |
A cycle of NREM and REM lasts about 90 minutes, repeating 4–6 times a night; N3 dominates early in the night and REM later. After REM deprivation (for example, after stopping sedatives or alcohol), REM rebound causes vivid dreams.
Sleep need: adults need 7 hours or more per night; children 6–12 years need 9–12 hours and teens 13–18 years need 8–10 hours.
Changes with aging: total sleep time is similar or slightly less, but N3 and REM decrease, night awakenings increase, sleep efficiency falls, and the circadian rhythm shifts earlier (advanced sleep phase — sleepy early in the evening and waking early in the morning). Nocturia, pain, medications, and napping add to the problem.
| Disorder | Key features |
|---|---|
| Insomnia | Difficulty falling asleep, staying asleep, or waking too early, with daytime impairment, at least 3 nights a week for 3 months (chronic) |
| Obstructive sleep apnea (OSA) | Repeated upper airway collapse; loud snoring, witnessed pauses in breathing, gasping, excessive daytime sleepiness, morning headache; linked to obesity, hypertension, dysrhythmias, stroke |
| Restless legs syndrome | Urge to move the legs with unpleasant sensations, worse at rest and in the evening, relieved by movement; associated with iron deficiency, kidney disease, pregnancy |
| REM sleep behavior disorder | Loss of REM atonia → acting out dreams (talking, kicking, punching); injury risk; can precede Parkinson's disease |
| Narcolepsy | Sudden sleep attacks, cataplexy, sleep paralysis, hallucinations at sleep onset |
| Circadian rhythm disorders | Shift work, jet lag, advanced or delayed sleep phase |
| Parasomnias | Sleepwalking, night terrors (N3), enuresis |
| Tool | Purpose |
|---|---|
| Pittsburgh Sleep Quality Index (PSQI) | Self-report of sleep quality over the past month (19 items grouped into 7 component scores) |
| Insomnia Severity Index | Severity of insomnia symptoms |
| Epworth Sleepiness Scale | Daytime sleepiness — likelihood of dozing in 8 everyday situations |
| STOP-Bang | Screening for OSA risk |
| Actigraphy | Wrist device that records movement to estimate sleep-wake patterns over days to weeks in the client's normal environment |
| Polysomnography | Overnight laboratory study recording brain waves (EEG), eye movements (EOG), muscle activity (EMG), heart rhythm, airflow, respiratory effort, SpO₂, and leg movements — the gold standard for OSA and many sleep disorders |
| Home sleep apnea test | Simplified airflow and oximetry study for suspected uncomplicated OSA |
Preparing for polysomnography: avoid caffeine and alcohol the afternoon and evening before (and naps that day); wash hair and avoid hair products so electrodes stick; bring usual nightwear and take usual medications unless told otherwise.
| Drug class | Safety points |
|---|---|
| Benzodiazepines (e.g., lorazepam, temazepam) | Sedation, confusion, falls, dependence, withdrawal; respiratory depression with opioids or alcohol; avoid in older adults and in OSA; not for long-term use; FDA boxed warning (2020) for abuse, dependence, and withdrawal — taper, do not stop abruptly |
| "Z-drugs" (zolpidem, eszopiclone, zaleplon) | Next-morning impairment (lower doses for women); avoid in older adults (Beers Criteria); complex sleep behaviors such as sleepwalking or sleep-driving (boxed warning) — stop if they occur; falls; take only when able to stay in bed 7–8 hours |
| Orexin receptor antagonists (suvorexant, lemborexant) | Next-day drowsiness; contraindicated in narcolepsy |
| Sedating antidepressants (trazodone, low-dose doxepin) | Orthostatic hypotension, priapism (trazodone) |
| Sedating antihistamines (diphenhydramine) | Anticholinergic — confusion, urinary retention, constipation, falls; avoid in older adults |
| Melatonin | Useful mainly for circadian problems; supplement content varies |
All hypnotics add to the central nervous system depression of alcohol and opioids — combining them can cause dangerous sedation and respiratory depression.
Hypnotic safety: never combine with alcohol or opioids; do not drive the next morning if drowsy; rise slowly to prevent falls; do not stop long-term benzodiazepines abruptly.
Shift workers: caffeine early in the shift rather than toward the end; bright light during the night shift; dark, quiet bedroom (blackout curtains) and a consistent sleep block after work; plan rest before driving home.
OSA: use CPAP every night; clean the mask and tubing; weight loss; avoid alcohol and sedatives; sleep on the side.
| Concern | Why it matters |
|---|---|
| Untreated OSA | Hypertension, atrial fibrillation, stroke, motor vehicle crashes; opioid-induced respiratory depression after surgery |
| Hypnotic use in older adults | Falls, hip fracture, delirium |
| Complex sleep behaviors on Z-drugs | Injury, sleep-driving — stop the drug |
| Sleep deprivation in hospital | Delirium, impaired healing, pain sensitivity |
| Dream enactment | Injury to client or bed partner |
| Excessive daytime sleepiness | Drowsy driving — advise not to drive until treated |
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