This DSM-5-TR chapter groups disorders characterized by repetitive thoughts or behaviors that the person feels driven to perform. They were separated from anxiety disorders in DSM-5, although anxiety is often prominent.
Core concepts
- Obsessions: recurrent, intrusive, unwanted thoughts, urges, or images that cause marked anxiety or distress (e.g., contamination, harm, doubt, symmetry, taboo thoughts). The person tries to ignore, suppress, or neutralize them
- Compulsions: repetitive behaviors (washing, checking, ordering) or mental acts (counting, praying, repeating words) performed to reduce the distress caused by obsessions or to prevent a feared event. They give short-term relief but maintain the disorder through negative reinforcement
- Symptoms are time-consuming (more than 1 hour a day) or cause significant distress or impairment
Neurobiology — dysfunction of the cortico-striato-thalamo-cortical (frontal–striatal–thalamic) circuit, involving the orbitofrontal cortex, anterior cingulate, and caudate; serotonin dysregulation (the basis for SSRI response), with glutamate and dopamine contributions. Genetic factors are significant. Childhood-onset cases can follow streptococcal or other infections (PANS/PANDAS) in a subset.
Disorders in this chapter
| Disorder | Key features |
|---|
| Obsessive-compulsive disorder (OCD) | Obsessions, compulsions, or both. Insight specifier: good or fair / poor / absent insight with delusional beliefs; tic-related specifier |
| Body dysmorphic disorder (BDD) | Preoccupation with perceived defects in appearance that are not observable or appear slight to others; repetitive behaviors (mirror checking, grooming, skin picking, reassurance-seeking, comparing). Muscle dysmorphia specifier. High rates of suicidal ideation; cosmetic procedures rarely help and often worsen distress |
| Hoarding disorder | Persistent difficulty discarding possessions regardless of value, due to a perceived need to save them and distress at discarding; clutter makes living areas unusable. Specifier: with excessive acquisition |
| Trichotillomania (hair-pulling disorder) | Recurrent hair pulling causing hair loss, with repeated attempts to stop |
| Excoriation (skin-picking) disorder | Recurrent skin picking causing lesions, with repeated attempts to stop |
| Substance/medication-induced; due to another medical condition; other specified (e.g., body-focused repetitive behavior such as nail biting or lip biting, obsessional jealousy) | — |
Tooth grinding (bruxism) is not a disorder in this chapter; sleep-related bruxism is classified with sleep-related movement conditions.
Distinguish from obsessive-compulsive personality disorder (OCPD) — a pervasive pattern of perfectionism, rigidity, and control that the person usually sees as appropriate (ego-syntonic), without true obsessions and compulsions. OCD symptoms are typically ego-dystonic (recognized as excessive).
- Content, frequency, and triggers of obsessions; type of rituals; time spent daily; degree of distress and interference with work, school, relationships, and self-care (key measures of severity)
- Insight level; avoidance patterns; family accommodation (relatives participating in rituals)
- Physical consequences: chapped, cracked, bleeding, or infected hands from washing; skin lesions and infection from picking; alopecia, and trichobezoar (hair ball causing GI obstruction) if hair is swallowed; falls, fire hazards, pests, and poor sanitation in hoarding
- Depression and suicide risk (especially BDD), tics, substance use, eating disorders
- Older adults who hoard: self-neglect, fall and fire risk, possible cognitive impairment
| Tool | Use |
|---|
| Yale-Brown Obsessive Compulsive Scale (Y-BOCS); children's version (CY-BOCS) | Severity; tracks treatment response |
| Body Dysmorphic Disorder Questionnaire | BDD screening |
| Saving Inventory-Revised; Clutter Image Rating | Hoarding severity |
| Home safety assessment | Hoarding (exits, fire, sanitation, structural safety) |
| Medical and neurologic exam; streptococcal testing if abrupt pediatric onset | Secondary causes |
| ECG before clomipramine | Conduction abnormalities |
Psychotherapy — first-line
- Exposure and response prevention (ERP): graded exposure to the feared trigger (e.g., touching a "contaminated" object) while resisting or delaying the compulsion; anxiety rises, then declines without the ritual, and the client learns the feared outcome does not occur
- CBT with cognitive restructuring (inflated responsibility, overestimation of threat, need for certainty)
- Habit reversal training for trichotillomania and excoriation disorder: awareness training, competing response (e.g., clenching fists, holding a stress ball), and social support; stimulus control (gloves, covering mirrors, keeping nails short)
- CBT for hoarding: motivation enhancement, sorting and decision-making skills, gradual discarding practice, reduced acquiring — done collaboratively with the client
- CBT for BDD: exposure, reducing mirror checking and camouflage, perceptual retraining
Medications
| Drug | Key points |
|---|
| SSRIs (first-line: fluoxetine, fluvoxamine, sertraline, paroxetine, escitalopram) | Fluoxetine, fluvoxamine, sertraline, paroxetine, and clomipramine are FDA-approved for OCD; escitalopram is used off-label. OCD often needs higher doses than depression and a longer trial (8–12 weeks) before judging response. Adverse effects: GI upset, insomnia, sexual dysfunction, hyponatremia, bleeding risk; boxed warning for suicidality under 25; serotonin syndrome; taper to stop. Fluvoxamine strongly inhibits CYP1A2 — dangerous with tizanidine and raises clozapine and theophylline levels |
| Clomipramine (TCA) | Effective for OCD; anticholinergic effects, sedation, orthostatic hypotension, weight gain, seizure risk (dose-related), cardiac conduction delay; lethal in overdose; never within 2 weeks of an MAOI |
| Antipsychotic augmentation | Low-dose risperidone or aripiprazole for partial SSRI response; monitor metabolic effects and EPS |
| Benzodiazepines | Not effective for OCD symptoms |
Procedures for severe refractory OCD: deep transcranial magnetic stimulation (FDA-cleared for OCD) and, in specialized centers, deep brain stimulation.
Listed in priority order.
- Physical safety and basic needs
- Treat skin damage from washing or picking (gentle cleansers, emollients, wound care, infection monitoring)
- Ensure nutrition, hydration, sleep, and hygiene are not displaced by rituals
- Assess suicide risk, particularly in BDD and with comorbid depression
- Do not abruptly block rituals — forcibly stopping a compulsion causes severe anxiety. Early in care, allow time for rituals within a structured daily schedule, then gradually limit them in agreement with the client and the treatment plan
- Support ERP as planned by the team — encourage graded exposure and delaying the ritual; praise effort; do not physically restrain the client from rituals or use punishment
- Therapeutic communication
- Acknowledge the distress ("You seem very worried that someone could get in"), explore feelings, and help identify triggers
- Avoid arguing about the logic of obsessions or giving repeated reassurance ("That's not true, don't worry") — reassurance acts like a compulsion and keeps the cycle going
- Explore coping alternatives together
- BDD — validate the distress without confirming or debating the perceived flaw; explore thoughts and feelings; support CBT and discourage repeated cosmetic procedures
- Hoarding
- Priority is safety (fire exits, falls, sanitation) — assess the home with the client and negotiate small, concrete changes first
- Never discard items without consent or organize forced clean-outs; they damage trust and are followed by rapid re-accumulation
- Coordinate with community services (adult protective services, housing, fire safety) when there is serious risk
- Hair pulling and skin picking — identify antecedent situations and emotions (boredom, stress, perfectionism), teach competing responses, keep hands busy, and provide wound care
- OCD is a medical condition linked to brain circuits — not a character flaw; effective treatment exists
- ERP works by facing fears without performing rituals; anxiety drops with practice
- SSRIs need 8–12 weeks at an adequate dose to reduce OCD symptoms and often need higher doses; do not stop suddenly; report worsening mood or suicidal thoughts
- Clomipramine: rise slowly (dizziness), manage dry mouth and constipation, avoid alcohol, report palpitations or seizures, store safely
- Family: reduce accommodation (joining rituals, giving constant reassurance) gradually and supportively; avoid criticism
- Hoarding: set small, achievable goals (one area, one category at a time)
- Skin and hair: keep nails short, use gloves or bandages as barriers, moisturize after necessary handwashing
| Complication | What to watch for |
|---|
| Suicide | BDD, severe OCD with depression, hopelessness |
| Skin infection, cellulitis | Excessive washing, picking |
| Trichobezoar | Abdominal pain, vomiting, obstruction in hair eaters |
| Home hazards | Fire, falls, infestations, blocked exits, eviction (hoarding) |
| Clomipramine toxicity | Seizures, dysrhythmias, wide QRS |
| Serotonin syndrome | Agitation, hyperthermia, clonus with combined serotonergic drugs |
| Social and occupational decline | Hours spent on rituals, avoidance |
- Compulsions reduce the anxiety caused by obsessions — relief reinforces the cycle
- Severity = time consumed (more than 1 hour/day) and interference with daily functioning
- ERP = graded exposure + resisting/delaying the ritual — the key psychotherapy
- SSRIs first-line; higher doses and 8–12-week trials; clomipramine is an alternative (seizures, cardiac toxicity)
- Circuit: frontal–striatal–thalamic dysfunction; serotonin
- Do not abruptly stop rituals early in care; schedule and gradually limit
- Avoid arguing and repeated reassurance; acknowledge feelings
- BDD: perceived flaw not observable to others; high suicide risk; cosmetic surgery does not help
- Hoarding: never discard without consent; safety first, small negotiated steps
- Trichotillomania and excoriation → habit reversal training
- OCD is ego-dystonic; OCPD is ego-syntonic perfectionism without true rituals
Country Notes
United States
- Hoarding with self-neglect in older adults may be referred to adult protective services and local fire or code agencies; procedures vary by state and locality.
- Deep TMS devices are FDA-cleared for OCD as an adjunct treatment.
Philippines
- The Mental Health Act (Republic Act 11036, 2018) requires informed consent and the least restrictive intervention — community interventions for hoarding should be collaborative.
- The NCMH Crisis Hotline (1553 from landlines) is available 24 hours for clients with suicidal thoughts; check the NCMH website for the mobile numbers.