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K - Kilograms (convert weight)
N - Note the dose range
C - Calculate carefully
C - Check against safe parameters
A 2-year-old refuses liquid amoxicillin. The nurse should: offer choices (cup vs. syringe), provide positive reinforcement, and consider mixing with a small amount of applesauce if not contraindicated. Never force medication or use restraints unless absolutely necessary.
| Concept | Pediatric Consideration | Adult Difference |
|---|---|---|
| Dosing Frequency | Often requires more frequent dosing due to faster metabolism | Standard intervals (BID, TID, QID) |
| Absorption Rate | Slower gastric emptying in infants affects absorption | Predictable absorption patterns |
| Liver Metabolism | Immature liver enzymes require dose adjustments | Fully developed enzyme systems |
S - Size appropriate (check weight/age)
A - Accurate calculation
F - Family education
E - Evaluate effectiveness
Child weighs 15 kg. Medication ordered: 10 mg/kg/day divided BID. How much per dose?
Solution: 15 kg × 10 mg/kg = 150 mg/day ÷ 2 doses = 75 mg per dose
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