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Patient reports: "I haven't slept well in weeks, lost 15 pounds, can't concentrate at work, and feel like a burden to my family." This indicates multiple MDD criteria and requires immediate assessment for suicidal ideation.
| Aspect | Depression | Mania |
|---|---|---|
| Mood | Sad, hopeless, empty | Elevated, irritable, euphoric |
| Energy | Low, fatigued | High, hyperactive |
| Sleep | Too much or insomnia | Decreased need (2-3 hours) |
| Speech | Slow, soft, minimal | Rapid, loud, pressured |
| Thinking | Slow, indecisive | Racing thoughts, distractible |
Question: When is suicide risk highest in depressed patients?
Answer: When depression begins to lift and energy returns, typically 2-3 weeks into antidepressant treatment.
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